Spike after 700 days
Yale researchers recognise post-vaccination syndrome (PVS)Press release from Yale, Feb 19, 2025
https://news.yale.edu/2025-02-19/Immune markers of post vaccination syndrome indicate future research directions
Immunological and Antigenic Signatures Associated with Chronic Illnesses after COVID-19 Vaccination
https://www.medrxiv.org/content/10.1101/2025.02.18.25322379v1
Chronic symptoms that developed a day or two soon after receiving a COVID-19 vaccine,
can become more severe in the days that follow,
PVS, little-understood, persistent condition,
remains unrecognized by medical authorities.
Common chronic symptoms of PVS
Excessive fatigue (85%)
Tingling and numbness (80%)
Exercise intolerance (80%)
Brain fog (77.5%)
Difficulty concentrating or focusing (72.5%)
Trouble falling or staying asleep (70%)
Neuropathy (70%)
Muscle aches (70%)
Anxiety (65%)
Tinnitus (60%)
Burning sensations (57.5%).
Getting out of breath
Palpitations
Headache
Dizziness
Lower quality of life scores
Mechanisms
Vaccine-induced immune responses may be triggering the stimulation of autoreactive lymphocytes.
Unregulated stimulation of innate immunity could lead to chronic inflammation.
Participants with PVS have a distinct set of autoantibodies.
A subset of non-classical monocytes has been shown to harbor S protein in patients with PVS
Biodistribution studies on mRNA–LNP platforms in indicate its ability to cross the blood-brain barrier,
and the local S expression could result in neurocognitive symptoms.
Compared with controls
PVS had reduced circulating memory and effector CD4 T cells,
and an increase in TNFα+ CD8 T cells.
Serological evidence of recent Epstein-Barr virus (EBV) reactivation, more frequent in PVS.
Measured levels of SARS-CoV-2 spike protein
Participants with PVS had significantly higher circulating S1 levels compared with the control group (p = 0.01).
PVS, (even those without evidence for infection), higher levels of spike protein than controls.
Detectable S1 was found in participants' plasma ranging from 26 to 709 days from the most recent known vaccination.
“That was surprising, to find spike protein in circulation at such a late time point,”
(Some PVS patients didn’t have any measurable spike protein).
Autoimmunity, tissue damage, Epstein-Barr Virus (EBV) reactivation, (infectious mononucleosis)
https://www.medrxiv.org/content/Immunological and Antigenic Signatures Associated with Chronic Illnesses after1 COVID-19 Vaccination.pdf
Yale LISTEN study.
LISTEN stands for Listen to Immune, Symptom and Treatment Experiences Now.
https://medicine.yale.edu/ycci/listen-study/
42 LISTEN PVS patients (some never infected)
22 who did not report any PVS symptoms after COVID-19 vaccination.
“It’s clear that some individuals are experiencing significant challenges after vaccination. Our responsibility as scientists and clinicians is to listen to their experiences, rigorously investigate the underlying causes, and seek ways to help,” Receive SMS online on sms24.me
TubeReader video aggregator is a website that collects and organizes online videos from the YouTube source. Video aggregation is done for different purposes, and TubeReader take different approaches to achieve their purpose.
Our try to collect videos of high quality or interest for visitors to view; the collection may be made by editors or may be based on community votes.
Another method is to base the collection on those videos most viewed, either at the aggregator site or at various popular video hosting sites.
TubeReader site exists to allow users to collect their own sets of videos, for personal use as well as for browsing and viewing by others; TubeReader can develop online communities around video sharing.
Our site allow users to create a personalized video playlist, for personal use as well as for browsing and viewing by others.
@YouTubeReaderBot allows you to subscribe to Youtube channels.
By using @YouTubeReaderBot Bot you agree with YouTube Terms of Service.
Use the @YouTubeReaderBot telegram bot to be the first to be notified when new videos are released on your favorite channels.
Look for new videos or channels and share them with your friends.
You can start using our bot from this video, subscribe now to Spike after 700 days
What is YouTube?
YouTube is a free video sharing website that makes it easy to watch online videos. You can even create and upload your own videos to share with others. Originally created in 2005, YouTube is now one of the most popular sites on the Web, with visitors watching around 6 billion hours of video every month.
