mRNA and cancer
MRNA vaccines and cancerhttps://www.oncotarget.com/article/28827/text
Article investigates the potential association between modified mRNA (modRNA) COVID-19 vaccinations and the development of haematopoietic cancers.
Censorship in science
https://www.oncotarget.com/article/28829/text
Only relentless determination gets dissenting data published in peer-reviewed journals
https://panagispolykretis.substack.com/p/only-relentless-determination-gets
Case Study
Healthy, young, athletic woman who,
developed acute lymphoblastic leukaemia (ALL) and lymphoblastic lymphoma (LBL),
following her second dose of the Pfizer/BioNTech COVID-19 vaccine (Comirnaty®), (July 2021)
Drugs and Total Body Irradiation (TBI)
April, 2025, cell transplant from an unrelated donor.
Part of an expanding body of literature documenting similar occurrences after modRNA vaccinations.
30 papers describe malignancies that developed in close temporal relationship
with modRNA COVID-19 vaccinations.
(Often just a few days)
with 28 focusing on haemato-lymphoproliferative disorders.
In lymphoma, 4 cases, four cases showed onset at the inoculation site, three cases manifested in draining lymph nodes
Japan, leukaemia, breast, pancreatic, and lip/oral/ pharyngeal cancers increased significantly in 2022
https://pubmed.ncbi.nlm.nih.gov/38721172/
critical literature gap: the absence of population studies verifying cancer incidence by vaccination status in order to estimate the true cancer incidence or mortality increases following COVID-19 vaccination.
https://pubmed.ncbi.nlm.nih.gov/38933341/
‘technically pro-drug gene therapies encased in lipid
nanoparticles (LNPs), rather than natural naked mRNA.
Emerging evidence suggests that the biodistribution and persistence of modRNA, facilitated by lipid nanoparticles, can affect various tissues and organs,
including the bone marrow and other blood-forming organs.
Unfettered access through most tissues and organs,
Notably, modRNA vaccines exhibit a particular affinity for the bone marrow,
potentially influencing the immune system at multiple levels and,
triggering both autoimmune disorders and neoplastic processes.
By integrating clinical observations and current research,
we aim to provide valuable insights into the potential carcinogenic outcomes associated with modRNA vaccination.
Cancer causing Mechanisms
Toxic spike protein
Vaccine induced lasts for longer than natural spike
A double proline that confers greater stability.
Synthetic pseudouridines contained in the modRNA have shown mitochondrial toxicity
It has been demonstrated that this modification can
increase the likelihood of +1 ribosomal frameshifting
during translation,
resulting in the production of multiple peptide products with unexplored effects
(This obviously poses serious safety concerns as only a single antigen was supposed to be encoded by the modRNA, not many undefined peptides with unknown antigenic and autoimmune potential.)
LNPs exhibits intrinsic cytotoxicity.
Presence of LNP-encapsulated DNA contamination originating from residual plasmid DNA
DNA integration may include the risk of tumorigenisis if
insertion reduces the activity of a tumour suppressor
or increases the activity of an oncogene.
Vaccine induced T-cell immunosuppression, impairing cancer surveillance
Interaction between the S2 subunit of the spike protein and the oncosuppressor proteins p53, BRCA1, and BRCA2
The impairment in type I interferon (IFN) signalling
Increased Transforming Growth Factor Beta
(TGF-β) Production.
Vaccine begins to accumulate rapidly, particularly in the bone marrow,
between 30 minutes and 48 hours following intramuscular injection,
the concentration of radioactively labelled nanoparticles in the femoral bone marrow of rats increased by 7.9-fold.
Proposed vaccine-induced activation of innate immune
Pathways which induce proinflammatory cytokine production (e.g., IL-6).
This cytokine milieu activates the STAT3 pathway, which
promotes malignant T-cell proliferation, survival, and resistance to apoptosis in T-cell lymphoma.
Repeated vaccination may exacerbate overexpression and T-cell exhaustion,
impairing immune surveillance and enabling tumour
growth.
Repeated booster doses, correlating with increased levels of the immunosuppressive subtype immunoglobulin G4,
increasing immunosuppression and immune evasion. Receive SMS online on sms24.me
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