When a Pharma Giant Comes to Town: The Promise and Politics of Eli Lilly's LEAP District

In Lebanon, Indiana, Eli Lilly and the state of Indiana are building something that has never quite been done before: a purpose-built biotech corridor, anchored by billions in private investment and over $1 billion in public funding.

The promise: thousands of jobs, a life sciences talent pipeline, and a potential model for how major corporations and local communities can grow together.

The reality is more challenging:

– Displaced farmers.
– Questions about who really benefits from public subsidies flowing to a pharmaceutical giant.
– Political blowback.
– The challenge of training enough manufacturing techs and scientists before the facilities even open.
– And the deep uncertainty of whether a brand-new ecosystem can actually deliver on its ambitions.

This film asks: What does responsible ecosystem building actually look like? Who are the winners and losers? And what does it take for cities to compete…and for that growth to reach everyone?

The LEAP District is one anchor, but the episode also looks at what's working elsewhere: Ford's Michigan Central Innovation District in Detroit, Tulsa Innovation Labs (which raised $200 million in four years and is on track to create 70,000 tech jobs), and Chattanooga's intentional cluster strategy built on the country's first municipal fiber network.

The throughline: Every city can participate in the innovation economy, but only if it grows from the inside out, builds on what it already has, and brings government, business, and civic institutions together around a shared vision.

Featuring Harvard Business School's Chris Stanton alongside economic development leaders Chike Aguh, Nicholas Lalla, and Mayor Tim Kelly of Chattanooga, and filmed in Nov. 2025, this interview is part of the HBS BiGS Nashville Roundtable series on “3 Ways Business Can Drive Economic Mobility.” Receive SMS online on sms24.me

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